Synthetic Biodegradable Polymeric-Based Scaffolds for Bone Tissue Engineering Applications: A Review

Bone tissue engineering is a developing area which has various clinical applications such as bone replacement in the case of orthopaedic defects, stabilization of spinal segments, pseudoarthrosis treatment, and bone neoplasia and tumours. Since the last decade, Porous scaffolds have played a significant role in bone tissue applications. Synthetic biodegradable polymers such as poly(glycolic acid) (PGA), polylactic acid (PLA), and polylactide-glycolic acid (PLGA) extensively used in bone tissue engineering. Synthetic biodegradable polymers are considered as suitable materials for bone tissue engineering applications because of their unique chemical and physical properties such as controlled structure and good mechanical properties. This article reviews synthetic biodegradable polymers scaffolds and their advantages and drawbacks in bone tissue engineering.

کلیدواژه ها:

Bone tissue engineering ، Scaffolds ، Biodegradable polymers.