Nanoparticles toxicity and their effects on health

Nanotechnology is a rapidly growing science of producing and utilizing nano-sized particles that measure in nanometers. These nanomaterials are already having an impact on health care. Now-adays we are using nanoproducts in various fields. Their unique size-dependent properties makethese materials superior and indispensable as they show unusual physical, chemical and biological properties. The rapidly developing field of nanotechnology will result in new sources of this exposure, through inhalation, ingestion, and injection. Although nanomaterials are currently beingwidely used in modern technology, there is a serious lack of information concerning the human health and environmental implications of manufactured nanomaterials. Since these are relatively new particles, it is necessary to investigate their toxicological behavior. The objective of this review was to trace the cellular response to nanosized particle exposure. The application of some nanoparticles together with their range of toxic doses was also reviewed. Effect of used nanoparticles on cell membrane, mitochondrial function, prooxidant/antioxidant status, enzymeleakage, DNA, and other biochemical endpoints was elucidated. This paper highlights the need for caution during the use and disposal of such manufactured nanomaterials to prevent unintended environmental impacts.

کلیدواژه ها:

nanoparticles ، nanotoxicity ، cytotoxicity ، nanomaterials