MicroRNA-mediated Resistance to Plant Viruses

MicroRNAs (miRNAs) are 20-24 nucleotide small RNAs which are processed from nuclear-encoded transcripts.miRNAs control the expression of target transcripts by cleaving or translational inhibition of the target RNAs.Artificial microRNAs (amiRNAs) are modified endogenous miRNA precursors in which the miRNA: miRNA duplexis replaced with sequences to silence a target gene. amiRNAs are used as new transformation techniques in eukaryotesand have been proven to be more effective in specificity and stability than other RNA-mediated gene silencingmethods. amiRNA-based antiviral defense is an effective and new approach to engineer resistance to plant viruses.Here, we summarize the role of miRNAs in resistance to plant viruses.

کلیدواژه ها:

amiRNA ، Gene silencing ، miRNA ، Plant viruses ، Resistance