Epidemiology and clinical features of infective endocarditis: A retrospective study of 57 patients in a tertiary university hospital in Iran

  • سال انتشار: 1398
  • محل انتشار: اولین کنگره پژوهشی دانشجویان دانشگاه علوم پزشکی هرمزگان
  • کد COI اختصاصی: HUMS01_055
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 464
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نویسندگان

Salar Javanmard Barbin

Nursing Student, Young Researchers Club, Nursing and Midwifery Faculty, Islamic Azad University of Medical Sciences, Urmia, Iran.

Rahim Nejadrahim

MD, Assistant Professor, Department of Infectious Diseases, Faculty of Medicine, Urmia University of Medical Sciences, Urmia , Iran.

Saeed Saeedikia

MD, Faculty of Medicine, Urmia University of Medical Sciences, Urmia , Iran.

Hanieh Marandi

Medical Student, Faculty of Medicine, Urmia University of Medical Sciences, Urmia , Iran.

Negar Javanmard Barbin

MSc in Medical Parasitology, Faculty of Medicine, Urmia University of Medical Sciences, Urmia , Iran.

چکیده

Background: Infective endocarditis (IE) is a life-threatening infectious disease. In order to define the epidemiologic characteristics of infective endocarditis in our region, we studied infective endocarditis cases over a 7-year period in tertiary teaching and referral hospitals. Methods: Medical records of all hospitalized patients diagnosed with IE at teaching hospitals of Urmia University of Medical Sciences, Iran, from 2009 to 2016, were retrospectively reviewed. patients who met the modified Duke criteria for definite or possible IE were included. Results: The study included 57 patients (35 males, 22 females; mean age 40 years) who were diagnosed as having definite IE, according to the modified Duke criteria. 15 cases (26.31%) had Rheumatic heart diseases (RHD), 12 cases (21.06%) had End Stage Renal Disease (ESRD), 6 cases (10.53%) had Congenital Heart Disease (CHD), 10 cases (17.54%) had Injection Drug User (IDU) and 14 cases (24.57%) had no significant cardiac disease. The primary clinical manifestations that were observed included 48 cases with fever (84.2%), 35 cases with anemia (61.4%) and 6 cases (11.1%) with altered mental status. Of the total 57 patients, blood cultures were positive in 52(64.91%) of cases. the leading causative microorganism were Staphylococcus aureus, isolated in 19 cases (51.35%), followed by Gram negative bacilli in 6 cases (16.22%) and Streptococcus spp. in 12 cases (32.43%). In-hospital death occurred in 9 patients (16.7%). Conclusion: Changes in IE profile required continuous epidemiological updates. In this study, IE were most common in men. Staphylococcus aureus and streptococcus spp. Remain the most common etiologic agents. ESRD and IDU was important predisposing factors for IE.

کلیدواژه ها

Infective endocarditis, Epidemiology, Risk factors.

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