A review of the characteristics of human saliva drived exosomes

  • سال انتشار: 1403
  • محل انتشار: چهارمین همایش بین المللی زیست شناسی و علوم آزمایشگاهی
  • کد COI اختصاصی: ZISTCONF04_018
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 119
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نویسندگان

Hamid Cheshomi

Agricultural and Natural Resources Research and Education Station of Sabzevar, Khorasan RazaviAgricultural and Natural Resources Research and Education Center, AREEO, Mashhad, Iran Cellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran

Behzad Cheshmi

Professional Member of Maxillofacial Surgery, Implantology Research, and Biomaterial Foundation,Tehran, Iran.

Mohammad Hosseinzadeh hesari

Master of Nursing, Operating Room Department, Faculty of Paramedices, Sabzevar University ofMedical Sciences, Sabzevar, Iran.

چکیده

Salivary exosomes are extracellular vesicles (EVs) characterized by abundant CD۶۳ immunoreactivityon their surface. Based on size and protein composition, these exosomes can be classified into twocategories: exosomes I, with a mean diameter of ۸۳.۵ nm, and exosomes II, with a mean diameter of۴۰.۵ nm. This review aims to explore the features of these exosomes, including their origin,composition, and potential applications in medicine.The composition of salivary exosomes is invaluablenot only for diagnostic purposes but also for understanding the roles of their contents and components inthe fundamental pathophysiological processes of various diseases. As these EVs can cross epithelialbarriers, they are likely crucial in transporting diverse components from the bloodstream into saliva.Consequently, compared to other bodily fluids, salivary exosomes may serve as a more accessible andefficient tool for investigating the role of exosomes in disease diagnosis and treatment.

کلیدواژه ها

Salivary exosomes are extracellular vesicles (EVs) characterized by abundant CD۶۳ immunoreactivityon their surface. Based on size and protein composition, these exosomes can be classified into twocategories: exosomes I, with a mean diameter of ۸۳.۵ nm, and exosomes II, with a mean diameter of۴۰.۵ nm. This review aims to explore the features of these exosomes, including their origin,composition, and potential applications in medicine.The composition of salivary exosomes is invaluablenot only for diagnostic purposes but also for understanding the roles of their contents and components inthe fundamental pathophysiological processes of various diseases. As these EVs can cross epithelialbarriers, they are likely crucial in transporting diverse components from the bloodstream into saliva.Consequently, compared to other bodily fluids, salivary exosomes may serve as a more accessible andefficient tool for investigating the role of exosomes in disease diagnosis and treatment.

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