Application of Ultrasonic Waves in Detection of a Circulating Tumor Cell (CTC) in the Blood

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 688

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شناسه ملی سند علمی:

ISAV09_072

تاریخ نمایه سازی: 11 دی 1398

چکیده مقاله:

The real, inexpensive, and long-term solution to cancer is prevention, but for people who have currently developed cancer, early diagnosis is of undeniable significance. Circulating tumour cells (CTCs) in the blood are among the earliest signs of cancer initiation or its metastasis; therefore, their detection can be a boon to the medical society and the patients in terms of treatment ease and survival. This study focuses on the use of ultrasonic waves and compressive sensing to detect CTCs in a random distribution of red blood cells (RBCs) in the plasma. This preliminary effort is made to identify the challenges of detecting CTCs in circulating blood. The results show that identification of CTCs is successful given accurate data of total and background pressure fields in the imaging domain and at the receivers. But, in the absence of accurate background data at the location of the receivers, the image is lost. The probable rea-sons for such an observation are discussed and a potential solution is suggested for future re-search to address this problem.

نویسندگان

Ashkan Ghanbarzadeh Dagheyan

Mechanical Engineering Department, Sharif University of Technology, Azadi Avenue, ۱۱۳۶۵-۱۱۱۵۵, Tehran, Iran.

Mohammad-Taghi Ahmadian

Mechanical Engineering Department, Sharif University of Technology, Azadi Avenue, ۱۱۳۶۵-۱۱۱۵۵, Tehran, Iran.

Bijan Vosoughi-Vahdat

Electrical Engineering Department, Sharif University of Technology, Azadi Avenue, ۱۱۳۶۵-۱۱۱۵۵, Tehran, Iran.

Anooshe Ghanbarzadeh Dagheyan

Mechanical Engineering Department, Sharif University of Technology, Azadi Avenue, ۱۱۳۶۵-۱۱۱۵۵, Tehran, Iran.