Quantitative Investigation of biological activity, mechanism and Toxicity offluorescence quenchers as a CO2reductant through the tetrakis (4-sulfonatophenyl) porphyrin (TSPP)

Tetrakis-(4-sulfonatophenyl) porphyrin is a high Potential molecule because ithas many applications in different fields like photocatalytic and catalytic reactions, photosensitizer and also many studies has done before on application of porphyrins in photoredox system as a catalyst for converting a number of organic compounds like CO2[1,2] . In this study,23 quenchers have been collected base on the antiseptic and anti-infective activities. The quantitativeactivities have been taken from PASS software. It is asoftware that have good ability to predict biological, toxicity and mechanism of molecules by structure. Each biological activities or mechanism which is higher than 50% is valuable for us. As seen in the table 2, 6-antracenedisulfonate: [ADS],2-naphthalenesulfonate: [2-NS] and 2-anthracenesulfonate: [2-AS]have shown maximum antiseptic and anti-infective ability from 87.8percent for [ADS] to lowest value equal to 50.7 Congo Red[CongoR] .According to the toxicity of all molecules in the table,[ARS] has shown activity probability (Pa) equal to 29.2 for mutagenic (T1) and 27.8 for skin irritation (T2).As a conclusion from the point of view of biologicalactivity [ADS] is better than [2-NS] but if we look at toxicity amounts it show lower than that for [ADS] so among these molecules [2-NS] is the best choice.