Samira Jahantigh - Department of Chemistry, Faculty of Science, University of sistan and bluchestan, Zahedan, Iran
Mahboobeh Rezaie Kakhaie - Department of Chemistry, Faculty of Science, University of Sistan and Baluchistan, Zahedan, Iran
Nourrollah Hazeri - Department of Chemistry, Faculty of Science, University of Sistan and Baluchistan, Zahedan, Iran

Recently, tetrahydrobenzo[b]pyran derivatives are known as an important class of heterocyclicscaffolds in the field of drugs and pharmaceuticals [1]. These compounds exhibit significantbiological properties such as antibacterial, antitumor, anti-allergic, antibiotic, hypolipidemicand immunomodulating activates [1-3]. In this paper, we want to report a one pot reactionfor the synthesis of tetrahydrobenzo[b]pyran derivatives using dimedone (1 mmol),malonitrile (1 mmol), aldehyde (1 mmol) in the presence of a catalytic amount (20 mol%) ofCo(NO₃)₂.6H2O in EtOH: H2O at 70 °C. The advantages of this method are simple work-up,short reaction time, high yields and using eco-friendly metal.