Urea-based porous organic polymer/graphene oxide hybrid as a highly efficient sorbent for bovine serum albumin

  • سال انتشار: 1397
  • محل انتشار: بیستمین کنگره شیمی ایران
  • کد COI اختصاصی: IRANCC20_270
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 386
دانلود فایل این مقاله

نویسندگان

Mahboobeh Ghazagh Miri

Department of Chemistry, Faculty of Sciences, University of Zabol, Zabol, Iran

Mostafa Khajeh

Department of Chemistry, Faculty of Sciences, University of Zabol, Zabol, Iran

Ali Reza Oveisi

Department of Chemistry, Faculty of Sciences, University of Zabol, Zabol, Iran

Mousa Bohlooli

Department of Chemistry, Faculty of Sciences, University of Zabol, Zabol, Iran

چکیده

In this work, a porous organic polymer (POP) was prepared via the reaction of tetrakis(4-aminophenyl)methane and 1,4-Phenylene diisocyanate [1]. The polymer was then combined with graphene oxide (GO) [2], to prepare POP/GO as a novel and highly efficient sorbent for pre-concentration and extraction of serum albumin samples, the most abundant protein in plasma [3], prior to spectrophotometric determination. Parameters which influence the extraction efficiency such as the amount of the adsorbent, pH of sample solution, ionic strength, adsorption and desorption time were investigated and optimized. Detection limit of the method 0.068 mg L-1 and determination coefficients (R2) of 0.9991 were obtained. The intra- and inter-day was calculated with five replicates in the same day and seven consecutive days, respectively. Intra-day and inter-day precisions were 1.7% and 5.9%, respectively. The maximum sorption capacity was 357.1 mg g-1. The proposed method was demonstrated to be sensitive enough for determination of serum albumin from biosamples.

کلیدواژه ها

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.