Effective Medical Treatment for Treating Symptomatic Adenomyosis

  • سال انتشار: 1397
  • محل انتشار: سومین کنگره بین المللی روش های کم تهاجمی زنان و مامایی ایران
  • کد COI اختصاصی: LAMOGMED03_082
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 465
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نویسندگان

Somayeh Fallah

MSc of Midwifery Faculty Member of Nursing and Midwifery school, Qazvin University of Medical Science, Qazvin, Iran

Masoumeh Dadashaliha

Gynecologist & obstetrics, Faculty Member of Medicine School, Qazvin University of Medical Science, Qazvin, Iran

Zahra Bajalan

MSc of Midwifery Faculty Member of Nursing and Midwifery school, Qazvin University of Medical Science, Qazvin, Iran

چکیده

Background: Adenomyosis is a heterogeneous gynecologic condition with a range of clinical presentations, the most common being heavy menstrual bleeding and dysmenorrhea; however, patients can also be asymptomatic. Material & Methods: The aim of this review is to discuss the medical approach to the management of adenomyosis symptoms, including pain and abnormal uterine bleeding. This study was performed of a systematic literature using the keywords adenomyosis , treatment, and electronic databases PubMed, Cochrane, Embase, ProQuest and Science direct from 2010 to present.Result: The standard treatment of adenomyosis is hysterectomy, Medical therapies using suppressive hormonal treatments, such as continuous use of oral contraceptive pills, high-dose progestin, selective estrogen receptor modulators, selective progesterone receptor modulators, the levonorgestrel-releasing intrauterine device, aromatase inhibitors, danazol, and gonadotrophin receptor hormone agonists can temporarily induce regression of adenomyosis and improve the symptoms. But Microwave endometrial ablation (MEA) is a recently developed procedure that enables endometrial ablation. Oral Dienogest after the procedure has long been used to suppress endometrium development and reduce adenomyosis-related dysmenorrhea. However, some cases could be resistant to dienogest. The primary endpoints were reduction in pain recurrence and anemia. The secondary endpoint was a change in the adenomyosis lesion and its symptomatic recurrence.Conclusion: The combination of MEA and postoperative dienogest is useful for treating uterine adenomyosis with menorrhagia and dysmenorrhea.

کلیدواژه ها

Adenomyosis, medical treatment, Bleeding

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