EFFECTS OF VITAMIN D-FORTIFIED YOGURT IN COMPARISON TO ORAL VITAMIN D SUPPLEMENT ON HYPERLIPIDEMIA IN PRE-DIABETIC PATIENTS: A RANDOMIZED CLINICAL TRIAL

  • سال انتشار: 1397
  • محل انتشار: سومین کنگره بین المللی و پانزدهمین کنگره تغذیه ایران
  • کد COI اختصاصی: INC15_414
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 418
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نویسندگان

Seyed Mostafa Nachvak

Nutritional Sciences Department, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran

Roghayeh Mostafai

Nutritional Sciences Department, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran

Reza Mohammadi

Department of Food Science and Technology, School of Nutritional Sciences and Food Technology,Kermanshah University of Medical Sciences, Kermanshah, Iran

Parisa Niazi

Nutritional Sciences Department, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran

چکیده

Background and Aim: The purpose of this study was to determine the effect of vitamin D-fortified yogurt consumption and its comparison with oral vitamin D supplementation in serum lipid profile in pre-diabetic patients with hyperlipidemia. Methods: This study was performed on 60 pre-diabetes patients who were randomly divided into two groups: group A (recipient of fortified yogurt with 1000 IU vitamin D) and group B (recipient of oral vitamin D supplement in a dose of 1000 IU) for three months. The study variables were evaluated at baseline and end of intervention. Results: The within-group analysis of lipid indices showed a significant reduction in the mean serum triglyceride levels in the fortified yogurt group (P = 0.001) and oral supplement group (P< 0.001), Also, showed a significant reduction in mean serum total cholesterol, LDL-C (P < 0.001) and HDL-C (P = 0.01) in both groups. The between-group comparison analysis of mean lipid indices changes showed that serum level of Triglyceride in oral supplement group were significantly more than fortified yogurt group (P=0.03). However, no significant difference was observed in the mean changes in serum TC (P=0.63), LDL-C (P=0.93) and HDL-C (P=0.21) levels between the oral supplement group and the fortified yogurt group.Conclusion: Fortified yogurt is a better alternative strategy of supplement to reduce the prevalence of vitamin D deficiency and consequently to improve the serum lipid profile in hyperlipidemic individuals.

کلیدواژه ها

Vitamin D fortified yogurt, Vitamin D deficiency, Hyperlipidemia, Vitamin D supplement, Pre-diabetes, Iran

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