The Effect of Sumac Powder (Rhus Coriaria L) on Homocysteine and High-Sensitivity C-Reactive Protein in Patients with Type ۲ Diabetes Mellitus
- سال انتشار: 1403
- محل انتشار: نشریه بین المللی علوم تغذیه، دوره: 9، شماره: 1
- کد COI اختصاصی: JR_IJNS-9-1_009
- زبان مقاله: انگلیسی
- تعداد مشاهده: 43
نویسندگان
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Herbal Medicine Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
چکیده
Background: High-sensitivity C-reactive protein (hs-CRP), and homocysteine increase along with inflammation in type ۲ diabetes mellitus (T۲DM). The antioxidant properties of sumac might affect homocysteine and hs-CRP levels. We aimed to examine the effects of sumac powder (Rhus Coriaria L) on homocysteine and hs-CRP in patients with T۲DM.Methods: In a single-blinded, randomized controlled clinical trial, conducted in Ardekan city, Yazd, Iran; ۶۰ patients with T۲DM were randomly divided into ۲ groups to consume either low fat yogurt alone in the control group or along with ۶ (۲×۳ grams) grams of sumac powder daily in the intervention group, for ۳ months. Fasting blood samples were used to analyze the fasting blood sugar (FBS), serum homocysteine, and hs-CRP at the baseline and after ۹۰ days. P values < ۰.۰۵ were considered statistically significant.Results: Fifty-eight individuals (intervention n=۳۰, control n=۲۸) with a mean age of ۵۲.۳۰±۷.۰۵ years in the intervention, and ۵۱.۶۱±۷.۰۷ years in the control group, finished the study. No significant differences were seen for FBS (p=۰.۹۴) and homocysteine (p=۰.۶۹) changes between the groups; but hs-CRP changes were significantly different between the groups (p=۰.۰۳).Conclusion: Daily consumption of sumac powder for ۳ months may not have a reducing effect on FBS and serum homocysteine. This is while sumac may prevent increment of hs-CRP in patients with T۲DM.کلیدواژه ها
Sumac, Rhus Coriaria, Homocysteine, C-reactive protein, diabetes mellitusاطلاعات بیشتر در مورد COI
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