Evaluation of the Probable linkage between Cytomegalovirus and Type ۲ diabetes
- سال انتشار: 1400
- محل انتشار: مجله بین المللی میکروبیولوژی مولکولی و بالینی، دوره: 11، شماره: 1
- کد COI اختصاصی: JR_IJMCM-11-1_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 58
نویسندگان
Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
Department of Microbiology, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
چکیده
Some recent investigations, have suggested a probable linkage between cytomegalovirus (CMV) and developing diabetes. But still there is not enough literature to assess the rate of this association. To this purpose, in the present study for detecting CMV genome, serum samples of ۵۰ type ۲ diabetic patients as the test group with an optimized PCR reaction were tested. Sex, age and A۱C parameter related to this group were recorded too. The specificity of the PCR test was ۱۰۰% and its sensitivity was ۱۰۰ copy of the viral genome in the sample. The related results were compared with the control group that was included ۵۰ non-diabetic participants. The CMV genome did not find in None of these ۱۰۰ samples. No related effects were observed between sex or amount of A۱C and association of CMV genome in these patients. However, it seems that the age parameter is effective in this regard. Comparing these participants with some other similar research suggest that this association rate is not very high and the virus only in elderly age can be considered as a probable risk factor. Thus, for managing diabetes should be more concentrated on the well-known factors such as obesity or unhealthy lifestyle.کلیدواژه ها
Cytomegalovirus, Diabetes, Polymerase chain reaction (PCR), Herpesviridae, elderly age , lifestyleاطلاعات بیشتر در مورد COI
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