Evaluation of the Probable linkage between Cytomegalovirus and Type ۲ ‎diabetes ‎

Some recent investigations, have suggested a probable linkage between cytomegalovirus ‎‎‎(CMV) and developing diabetes. But still there is not enough literature to assess the rate of ‎‎this association. To this purpose, in the present study for detecting CMV genome, serum ‎samples ‎of ۵۰ type ۲ diabetic patients as the test group with an optimized PCR ‎ reaction ‎were ‎tested. Sex, age and A۱C parameter related to this group were recorded too. The ‎‎specificity of the PCR test was ۱۰۰% and its sensitivity was ۱۰۰ copy of the viral genome ‎‎in the sample. The related results were compared with the control group that was included ‎‎‎۵۰ non-diabetic participants. The CMV genome did not find in None of these ۱۰۰ samples. ‎‎No related effects were observed between sex or amount of A۱C and association of CMV ‎‎genome in these patients. However, it seems that the age parameter is effective in this ‎‎regard. Comparing these participants with some other similar research suggest that this ‎‎association rate is not very high and the virus only in elderly age can be considered as a ‎‎‎probable risk factor. Thus, for managing diabetes should be more concentrated on ‎the ‎‎well-known factors such as obesity or unhealthy lifestyle.‎

کلیدواژه ها:

Cytomegalovirus ، Diabetes ، Polymerase chain reaction (PCR)‎ ، Herpesviridae‎ ، elderly age ‎ ، lifestyle‎