Synthesis, feasibility study of production of singlet oxygen and hydroxyl radical and performance in antibacterial activity of ZnS:Eu QDs

  • سال انتشار: 1401
  • محل انتشار: فصلنامه کامپوزیت ها و ترکیبات، دوره: 4، شماره: 11
  • کد COI اختصاصی: JR_JRCC-4-11_002
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 155
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نویسندگان

Merat Karimi

Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran

Ehsan Sadeghi

Department of Physics, University of Kashan, Kashan, Iran

Samira Khosravi Bigdeli

Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran

Mostafa Zahedifar

Department of Physics, University of Kashan, Kashan, Iran

چکیده

ZnS:Eu nanoparticles also have the ability to produce reactive oxygen species that can be used to treat cancers. Eu doped zinc sulfide quantum dots (QDs) were prepared by the chemical Co-precipitation method. X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) and infrared Fourier transform (FT-IR) analysis were used to characterize the quantum dots. The photoluminescence spectrum (PL) of ZnS:Eu QD in excitation wavelength of ۲۸۰ nm shows two emission peaks at ۳۸۴ and ۷۱۵ nm. In order to use these QDs as photosensitizer in photodynamic therapy, anthracene and methylene blue chemical detectors were used for detection of singlet oxygen and hydroxyl radical, respectively. The significant point for these quantum dots is that, in addition to production of hydroxyl radical, they also have the ability to produce singlet oxygen with UV-C radiation. The antimicrobial effect of ZnS:Eu QDs was also investigated using a disc diffusion method on ۱۱ microbial strains. Zinc sulfide nanoparticles with Europium impurities can have good medical application due to their good antibacterial activity and ability to produce reactive oxygen species.ZnS:Eu nanoparticles also have the ability to produce reactive oxygen species that can be used to treat cancers. Eu doped zinc sulfide quantum dots (QDs) were prepared by the chemical Co-precipitation method. X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) and infrared Fourier transform (FT-IR) analysis were used to characterize the quantum dots. The photoluminescence spectrum (PL) of ZnS:Eu QD in excitation wavelength of ۲۸۰ nm shows two emission peaks at ۳۸۴ and ۷۱۵ nm. In order to use these QDs as photosensitizer in photodynamic therapy, anthracene and methylene blue chemical detectors were used for detection of singlet oxygen and hydroxyl radical, respectively. The significant point for these quantum dots is that, in addition to production of hydroxyl radical, they also have the ability to produce singlet oxygen with UV-C radiation. The antimicrobial effect of ZnS:Eu QDs was also investigated using a disc diffusion method on ۱۱ microbial strains. Zinc sulfide nanoparticles with Europium impurities can have good medical application due to their good antibacterial activity and ability to produce reactive oxygen species.

کلیدواژه ها

Nanoparticles, ZnS:Eu, Co-precipitation, Antibacterial, Cancer

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