The Effect of Resistance Training on Heart Damage Risk Factors in Adult Male Rats Exposed to Nandrolone
- سال انتشار: 1402
- محل انتشار: فصلنامه تغذیه، روزه داری و سلامت، دوره: 11، شماره: 2
- کد COI اختصاصی: JR_JNFH-11-2_007
- زبان مقاله: انگلیسی
- تعداد مشاهده: 220
نویسندگان
Department of Exercise Physiology, Shoushtar Branch, Islamic Azad University, Shoushtar, Iran.
Department of Exercise Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
چکیده
Introduction: Athletes and non-athletes use nandrolone (Na) for different purposes as a derivative of testosterone, and various results have been reported regarding its use. This study aimed to evaluate the effect of a period of resistance training (RT) on SOD, MDA, CRP, and cTn-C in the cardiac tissue of Na- exposed rats. Methods: In the present experimental research, ۲۰ male Wistar rats aged ۸-۱۰ weeks were randomly divided into four groups of five animals: (۱) control, (۲) sham, (۳) Na (۱۰mg/kg), (۴) Na+RT. The RT group performed ۱m ladder climbing in three sessions weekly for eight weeks. One-way ANOVA and Tukey’s post hoc tests were implemented to analyze the data (P≤۰.۰۵). Results: Levels of SOD were significantly lower in the Na+RT group compared to the control group (P=۰.۰۰۶). However, no significant difference was observed in levels of SOD in the Na group compared to the Na+RT group (P=۰.۹۹). In addition, the levels of MDA and CRP in the Na+RT group were significantly lower than in the Na group (P≤۰.۰۵). Histological studies showed that Na intoxication, RT, and RT with Na use did not affect tissue changes in the study groups. Conclusion: Based on the results, nandrolone with and without resistance training increases heart disease risk indicators. However, the risk of heart disease in training and abusing nandrolone is less than the normal condition of this steroid without training.کلیدواژه ها
Resistance training, Nandrolone, Heartاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.