Green Synthesis of Au-doped SnO۲ Nanoparticles Using Teucrium Polium Plant Extract for the Evaluation of Their Physicochemical and Antibacterial Properties
- سال انتشار: 1402
- محل انتشار: مجله علوم پیشرفته زیست پزشکی، دوره: 13، شماره: 2
- کد COI اختصاصی: JR_JABS-13-2_007
- زبان مقاله: انگلیسی
- تعداد مشاهده: 252
نویسندگان
Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran
Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran
Institute of Nanoscience and Nanotechnology, University of Kashan, Kashan, Iran
چکیده
Background & Objective: The biological production of nanoparticles (NPs) is a technique that has garnered a lot of interest because it is inexpensive, straightforward, and friendly to the natural environment. This study explores the green synthesis of Au-doped SnO۲ NPs using Teucrium polium plant extract and evaluates their antimicrobial properties in comparison with two commonly used antibiotics. Materials & Methods: Initially, an extract of Teucrium polium was made using water, and then it was combined with solutions of tin (II) chloride dehydrate [SnCl۲.۲H۲O] and gold (III) chloride trihydrate [HAuCl۴.۳H۲O]. The crystal structure was studied using X-ray diffraction (XRD). The form, structure, and grain size of the NPs were analyzed using scanning electron microscope (SEM) and transmission electron microscope (TEM). The synthesized NPs were tested for their antibacterial properties. Results: The XRD and EDS analyses revealed that the SnO۲:Au phase formed an average crystallite size of ۲۲ nm and an Au dopant content of around ۲%. The SEM and TEM investigations demonstrated that the NPs were formed in a regular and nanoscale manner, with diameters ranging from ۲۵ to ۳۰ nm. MIC and MBC of SnO۲: Au NPs against the studied bacteria(S.aureus ATCC ۴۳۳۰۰, P.aeruginosa PAO۱) were reported ۹.۶±۰.۱۳- ۹.۶±۰.۰۷ μg/mL and ۲۵.۹±۱۱.۵- ۳۲.۵±۱۱.۲ μg/mL Conclusion: Green-synthesized NPs exhibit significant antimicrobial activity against both Gram-positive and Gram-negative bacteria, even at low concentrations. The NPs effectively eliminate bacteria and prevent biofilm formation.کلیدواژه ها
Teucrium polium, Green synthesis, SnO۲: Au NPs, Structural analysis Antimicrobialاطلاعات بیشتر در مورد COI
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