The relationship between serum levels of interleukin ۲ and CRP and ESR in patients with covid-۱۹

  • سال انتشار: 1402
  • محل انتشار: چهارمین کنفرانس بین المللی یافته های نوین در علوم پزشکی و بهداشت با رویکرد ارتقای سلامت
  • کد COI اختصاصی: MSHCONG04_023
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 254
دانلود فایل این مقاله

نویسندگان

Akram Mobarakeh

Department of Experimental Sciences, Dezful Branch, Islamic Azad University, Dezful, Iran

Mohsen Pishbin

Department of Lung, Faculty of Medical Sciences, Dezful University of Medical Sciences, Dezful, Iran

Atousa Moradzadegan

Department of Experimental Sciences, Dezful Branch, Islamic Azad University, Dezful, Iran

Maysam Mard Soltani

Department of Clinical Biochemistry, Faculty of Medical Sciences, Dezful University of Medical Sciences, Dezful, Iran

Neda Shakerian

Department of Clinical Biochemistry, Faculty of Medical Sciences, Dezful University of Medical Sciences, Dezful, Iran

Ali Arianezhad

Clinical Research Development Unit, Ganjavian Hospital Dezful University of Medical Sciences, Dezful, Iran

چکیده

The inflammatory response is a critical factor in the pathogenesis of coronavirus disease ۲۰۱۹ (COVID-۱۹), wherein the excessive production of inflammatory cytokines exacerbates the severity of the disease. The present investigation sought to examine the associations that exist between interleukin-۲ (IL-۲), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) as they relate to the accurate prognostication of mild and severe incidents of COVID-۱۹. This research involved ۱۴۱ individuals divided into three categories: those with covid-۱۹ who were hospitalized in the ICU, patients who were hospitalized in acute care, and a group of healthy participants who served as a control. The findings of the study indicate that individuals with severe manifestations of Covid-۱۹ exhibited a reduction in serum IL-۲ levels in contrast to those with non-severe symptoms as well as the control group with no Covid-۱۹ infection. Furthermore, the outcomes of the study indicated significant discrepancies (p=۰.۰۰۱) in the average serum level, ESR, and CRP levels among the intensive care unit (ICU) group as compared to the acute and control groups. This investigation has demonstrated that the concentration of cytokines in the serum may serve as a warning and prognostic determinant of the severity of Covid-۱۹. The research findings suggest that a correlation may exist between diminished levels of interleukin-۲ and the prognostication of COVID-۱۹. The utilization of haematological and serological factors has been demonstrated to be an effective means of assessing the severity of illness and predicting the prognosis of patients diagnosed with COVID-۱۹.

کلیدواژه ها

COVID-۱۹, interleukin-۲, CRP, ESR

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.