Prevalence and antibiotic resistance pattern of Klebsiellapneumoniae isolated from burn patients in the North of Iran
- سال انتشار: 1401
- محل انتشار: بیست و سومین کنگره بین المللی میکروب شناسی ایران
- کد COI اختصاصی: MEDISM23_219
- زبان مقاله: انگلیسی
- تعداد مشاهده: 120
نویسندگان
Burn and regenerative medicine research center, Guilan University of medical sciences, Rasht, Iran
Burn and regenerative medicine research center, Guilan University of medical sciences, Rasht, Iran
Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Burn and regenerative medicine research center, Guilan University of medical sciences, Rasht, Iran
چکیده
Background and Aim : Klebsiella species are among the most common bacteria isolated fromburn wounds that cause severe complications in patients. In recent years, drug resistance in bacteriahas increased, associated with increased mortality and treatment costs. Therefore, determining theantibiotic resistance pattern to select the appropriate treatment and planning to prevent the spreadof this infection seems necessary. Thus, the present study investigates the prevalence of K.pneumonia isolates and antimicrobial resistance patterns for two years in a burn hospital in theNorth of Iran.Methods : This study was performed on burn patients hospitalized from March ۲۰۱۸ to March۲۰۲۰. Antibiotic susceptibility testing of all isolates was performed according to CLSI instructions,and the results were analyzed by SPSS software version ۲۴.Results : ۶۱ cases (۱۰.۲۷%) of K. pneumonia isolates were isolated from ۵۹۴ clinical specimens.The mean age of patients was ۳۹.۱۵ years. Five cases (۸.۲%) of these infections were related topatients with VAP. The highest antibiotic susceptibility was observed to azithromycin (۶۸.۲%),and the highest resistance to imipenem (۸۵.۷%) was observed.Conclusion : because of the high prevalence of resistance in Klebsiella specimens, seriousmeasures are necessary for prescribing antibiotics based on the antibiogram pattern. Infectiontreatment protocols based on laboratory results can prevent increased antibiotic resistance.کلیدواژه ها
Antibiotic resistance, Burn wound, Klebsiella pneumoniae, Nosocomial infectionمقالات مرتبط جدید
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