PROGNOSTIC FACTORS FOR SURVIVAL AT ۶-MONTH FOLLOW-UP OF HOSPITALIZED PATIENTS WITH DECOMPENSATED CONGESTIVE HEART FAILURE

  • سال انتشار: 1389
  • محل انتشار: مجله آریا آترواسکلروز، دوره: 6، شماره: 3
  • کد COI اختصاصی: JR_RYA-6-3_006
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 282
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نویسندگان

Mostafa Cheraghi

Cardiology Fellow, Isfahan University of Medical Sciences, Isfahan, Iran.

Masoumeh Sadeghi

Associate Professor of cardiology,Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical sciences, Isfahan ,Iran.

Aliakbar Tavassoli

Associate Professor of Cardiology, Isfahan School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Nizal Sarrafzadegan

Professor of Cardiology, Isfahan Cardiovascular Research Institute, Isfahan University of Medical sciences, Isfahan ,Iran.

Ali Pourmoghadas

Associate Professor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Mohammad Arash Ramezani

Community Medicine Specialist, Isfahan Cardiovascular Research Center, Isfahan, Iran.

چکیده

Abstract:BACKGROUND: The prevalence of Congestive Heart Failure (CHF) is increasing in recent years. Factors associated with mortality in CHF patients are important to be determined in order to select therapeutic modality by physicians. The purpose of the current study was to declare predictors of ۶-months survival in patients hospitalized for decompensated CHF in Isfahan.METHODS: A cohort of ۳۰۱ hospitalized patients with decompensated CHF were recruited in this study. The diagnosis of CHF was based on previous hospitalizations and Framingham criteria for heart failure (HF). Information regarding past history, accompanying diseases such as cerebrovascular accidents (CVA), chronic obstructive pulmonary diseases (COPD), clinical data, medications and echocardiography were obtained by a cardiologist. Patients were followed for their survival for ۶ months by telephone calls. Kaplan-Meier method was used for uni variate survival analysis and Cox proportional hazard model was used for multivariate analysis.RESULTS: Mean age of patients was ۷۱.۹ ± ۱۲.۲ years and ۵۹.۸% was male. During ۶-months follow-up ۱۳۸ (۴۵.۸%) patients died. Mean survival was ۱۱۹.۲ ± ۴.۴ days (Mean ± SEM). Significant prognostic factors for ۶ months survival were high education level (HR = ۰.۷۴, CI ۹۵% ۰.۵۹—۰.۹۳), COPD (HR = ۱.۹۱, CI ۹۵% ۱.۲—۳.۰۴), CVA (HR = ۱.۶۹, CI ۹۵% ۱.۰۳—۲.۷۸), Angiotensin Converting enzyme (ACE) inhibitors use (HR = ۰.۴۴, CI ۹۵% ۰.۳—۰.۶۶) and Diuretics (HR = ۰.۶۳, CI ۹۵% ۰.۴۱-۰.۹۶).CONCLUSION: Six-month survival of hospitalized decompensated CHF patients in Iran is not favorable. Many factors particularly accompanying diseases and medications affected the patient’s ۶-months survival.Keywords: Heart failure, Survival,  Mortality.

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