The effect of educational and encouraging interventions on anthropometric characteristics and perilipin-۱ levels: TABASSOM Study

  • سال انتشار: 1400
  • محل انتشار: مجله آریا آترواسکلروز، دوره: 17، شماره: 1
  • کد COI اختصاصی: JR_RYA-17-1_009
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 278
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نویسندگان

Maryam Maghroun

Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Noushin Mohammadifard

Assistant Professor, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Firoozeh Sajjadi

Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Narges Jafaridinani

Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Simin Karimi

Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Katayoun Rabiei

Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Soraya Massoudi

Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Nizal Sarrafzadegan

Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

چکیده

BACKGROUND: Perilipin protein located in lipid droplets is involved in formation and storage of lipid in adipocytes; thus, it is considered as one of the obesity biomarkers. This study was performed to examine the effect of educational and encouragement interventions and lifestyle modifications on anthropometric characteristics and perilipin-۱ level.METHODS: This quasi-experimental study was conducted on subsample of TABASSOM Study. Participants were ۴۲ overweight and obese children and adolescents aged ۶-۱۸ years old and ۸۰ overweight and obese adults aged ۱۹-۶۵ years old. Anthropometric characteristics including weight, height, waist circumference (WC), body fat percentage (BFP), and perilipin-۱ level were measured at the first and the end of study (after one year).RESULTS: After intervention, the mean of perilipin-۱ decreased significantly in total children and adolescents (before vs. after: ۲۶.۷۹ ± ۱۳.۱۷ vs. ۲۲.۵۷ ± ۸.۰۳; P = ۰.۰۰۶) and girls (۲۷.۷۵ ± ۱۰.۵۱ vs. ۲۲.۰۰ ± ۸.۱۵; P = ۰.۰۰۱), but decreasing was not significant in boys. In adults, perilipin-۱ levels were significantly reduced in total subjects (before vs. after: ۱۶.۱۹ ± ۱۳.۴۲ vs. ۱۵.۳۴ ± ۱۱.۲۵; P = ۰.۰۲۹) and men (۱۸.۰۲ ± ۱۵.۷۸ vs. ۱۵.۴۴ ± ۱۰.۶۱; P = ۰.۰۰۳). There was no significant difference in mean of body mass index (BMI), WC, and BFP in both groups after ۱۲ months.CONCLUSION: Educational and encouraging interventions and lifestyle modifications could lead to decreasing perilipin-۱ level in adults, children, and adolescents. 

کلیدواژه ها

Obesity, Overweight, Adult, Child, Adolescent, Perilipin-۱, Anthropometry

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