Sepideh Dolati - Department of Nutrition, Ministry of Health and Medical Education, Tehran, Iran.
Rokhsare Rostami - Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Seyed Ali Hosseini - Department of Sport Physiology, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran.
Alemeh Hariri Far - Department of Community Nutrition, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.
Abdossaleh zar - Department of Sport Sciences, Faculty of Literature and Human Sciences, Persian Gulf University, Boushehr, Iran.

Introduction: Diabetes is a disease caused by a lack of insulin secretion or a decrease in tissue sensitivity to insulin. The aim of this study was to investigate the lipid-lowering effects of endurance training (ET) with cinnamon (C) extract in streptozotocin (STZ)-induced diabetic rats.Methods: Thirty-two diabetic rats were divided into four groups of ۸ rats, including ۱) cinnamon, ۲) training, ۳) training+cinnamon and ۴) sham groups. During four weeks, groups ۱ and ۳ received daily ۱۰۰ mg/kg C perennially, and groups ۲ and ۳ ran on treadmill five times per week for ۶۰ minutes each session at a speed of ۸ to ۱۶ m/min. Data were analyzed using paired sample t test and one way ANOVA and Tukey’s post-hoc tests (p≤۰.۰۵).Results: cinnamon, training and training+cinnamon significantly reduced TG, LDL and VLDL levels as well increased HDL (P=۰.۰۰۱) in compare with sham group, training+cinnamon significantly reduced Cho and VLDL (P=۰.۰۰۱) in compare with sham group; training+cinnamon had more effect on decrease of Cho (p=۰.۰۲) and LDL (p=۰.۰۰۲) as well as increase of HDL (P=۰.۰۰۴) rather than training. Also cinnamon (P=۰.۰۳) and training (P=۰.۰۴) significantly reduced VLDL in compare with sham group.Conclusions: Although training and cinnamon have lipid-lowering effect in diabetic rats, nevertheless it seems training simultaneously with cinnamon administration has better effect on improving lipid profile compare to training alone.

Diabetes Mellitus, Cinnamomum zeylanicum, Lipids, Exercise, Endurance training