New outlook to vitamin D functions in dairy cows: non- classical roles
- سال انتشار: 1400
- محل انتشار: دوفصلنامه علوم و فنون دامپزشکی ایران، دوره: 13، شماره: 2
- کد COI اختصاصی: JR_IJVST-13-2_001
- زبان مقاله: انگلیسی
- تعداد مشاهده: 328
نویسندگان
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Center of Excellence in Ruminant Abortion and Neonatal Mortality, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
چکیده
In addition to the well-studied effects in regulating calcium and phosphorus balance, vitamin D has many non-calcemic effects that include acting as an immune modulator or an antioxidant. Cows acquire vitamin D either from photosynthesis in the skin or through swallowing fungi in the forage or vitamin D supplements. Although vitamin D deficiency is rare, today we are facing an increasing number of vitamin D deficiencies in cows due to the indoor housing away from sunlight exposure. According to the NRC recommendation, to maintain the vitamin D serum concentration in the range of ۲۰ to ۵۰ ng/ ml, it is necessary to administer ۲۱,۰۰۰ IU/ d of vitamin D in cattle. In addition, considering the involvement of vitamin D in various calcemic and non-calcemic effects, it seems that previously recommend levels of vitamin D supplementation have not been enough for preventing many diseases and disorders in cattle. Vitamin D toxicity may also occur due to over-supplementation of vitamin D or overgrazing in plants with high amounts of vitamin D metabolites. This review article will discuss various roles of vitamin D in dairy cattle health, normal physiology, and disease prevention.کلیدواژه ها
Calcitriol, Immune Modulation, oxidative stressاطلاعات بیشتر در مورد COI
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