Controlled Release of Triclosan and Its Effect on the Antibacterial Properties

سال انتشار: 1390
محل انتشار: کنفرانس بین المللی فرآورش پلیمرها
کد COI اختصاصی: PPSRC2011_112
زبان مقاله: انگلیسی
تعداد مشاهده: 1708

نویسندگان

Department of Chemical Engineering (Polymer group), Isfahan University of Technology

چکیده

In this study, Triclosan (2,4,4-trichloro-2-hydroxydiphenyl ether) was used for preparation of antibacterial polyethylene compound. Two masterbatches with 10% triclosan, based on polyethylene (PE) and maleic anhydride grafted polyethylene (PE-g-MA), were prepared by an internal mixer. Then, these masterbatches were diluted on PE matrix to 0.1%, 0.5%, and 1% triclosan using a twin screw extruder. The PE-g-MA was used to study polymer matrix polarity effect on triclosan release. In order to examine the effects of crystallization on triclosan release, the samples were cooled via three different cooling modes, isothermal, quench, and a moderate cooling rate. The release of triclosan from the polymer matrix was measured by UV-Vis absorption spectroscopy. The results showed that the samples which contained PE-g-MA had the highest triclosan release. Moreover, the samples which were cooled by quenching had the highest release of triclosan, while the lowest release was shown by isothermally cooled samples. The results showed that the triclosan-containing polyethylene possessed excellent antibacterial properties. Triclosan exhibited better inhibitory effects against the gram-positive bacteria compared to gram-negative bacteria. Furthermore, the presence of maleic anhydride increased antibacterial performance.

کلیدواژه ها

Triclosan, Polyethylene, Maleic anhydride grafted polyethylene, Controlled release, Antibacterial

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.