Two years study of prevalence and antibiotic resistance pattern of Gram-negative bacteria isolated from surgical site infections in the North of Iran
- سال انتشار: 1400
- محل انتشار: بیست دومین کنگره میکروب شناسی ایران (مجازی)
- کد COI اختصاصی: MEDISM22_076
- زبان مقاله: انگلیسی
- تعداد مشاهده: 174
نویسندگان
Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
چکیده
Background and Aim : Surgical site infections (SSIs) are a devastating complication of hospitalization and one of the global health problems The present study aimed to investigate the frequency and antibiotic susceptibility pattern of Gram-negative bacteria (GNB) isolated SSIs in the North of Iran.Methods : This cross-sectional study conducted over a two-year period during ۲۰۱۸-۲۰۲۰ on all cases of SSIs who had a positive culture for a GNB. Standard microbiological tests were followed for the bacterial isolation and identification. Antimicrobial susceptibility profiles were determined using disk diffusion method. Results : During the study period, a total of ۷۸ nonduplicated GNB isolated from SSIs. The most prevalent surgical procedures were fracture fixation (۳۷.۲%), and tissue debridement (۲۳.۱%). Klebsiella isolates showed the highest isolation rate (۲۹.۵%) followed by Enterobacter (۲۸.۲%), and Acinetobacter (۱۶.۷%). Antibiotic susceptibility results showed that Acinetobacter isolates were almost resistant to all of the tested antibiotics, except gentamicin, co-trimoxazole, and meropenem. Enterobacteriaceae isolates showed the lowest resistance against amikacin, co-trimoxazole, and imipenem. Overall, ۴۹ (۶۲.۸%) of isolates were multiple drug-resistant (MDR). Conclusion : In summary, a remarkable rate of MDR isolates which showed an increasing trend during recent years is a serious alarm for the management of SSIs caused by GNB. Moreover, the results of regional assessments, provide good epidemiological background for comparing our situation with other regions.کلیدواژه ها
Surgical site infection, Gram-negative bacteria, Antibiotic resistance, MDRاطلاعات بیشتر در مورد COI
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