Mehrnaz Mehdizadeh - Department of Chemistry, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, IRAN
Zahra Mansur Lakoraj - Department of Chemistry, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, IRAN
Pedram Rahimian - Department of Chemistry, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, IRAN
Sama Alizadeh - Department of Chemistry, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, IRAN
Babak Sadeghi - Department of Chemistry, Faculty of Science, Islamic Azad University, Tonekabon Branch, Tonekabon, IRAN

Combination therapy for the treatment of cancer is becoming more popular because it generates synergistic anticancer effects,reduces individual drug-related toxicity and suppresses multi-drug resistance through different mechanisms of action.[1] Especially,silver nanoparticles(AgNPs) have been extensively carried out biomedical are as because of their physicochemical,and biological therapeutic properties.Recent studies have shown that there are anti-fungal,anti-viral,anti-inflammatory,anti-angiogenic biological activities,especially anti-bacterial and anti-cancer features of silvernanoparticles.Recent researches demonstrate that multifunctional cytotoxic biological activities of biosynthesized silver nanoparticles can be used as an anti-cancer agent.[2] in fact,mentioned that,over time,bacteria evolved several resistance mechanisms against antibiotics, thus making treating infections caused by them extremely difficult.[3-6].

Nanosilver, Anti-angiogenic, Anti-inflammatory, Anti-bacterial, Anti-cancer