The Effect of Endurance Training with Garlic and Stevia Supplementation on AgRP and α-MSH in Brain Tissue of Obese Wistar Rats
محل انتشار: فصلنامه تغذیه و امنیت غذایی، دوره: 9، شماره: 2
سال انتشار: 1403
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 39
فایل این مقاله در 9 صفحه با فرمت PDF قابل دریافت می باشد
- صدور گواهی نمایه سازی
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JNFS-9-2_006
تاریخ نمایه سازی: 18 اردیبهشت 1403
چکیده مقاله:
Background: The aim of this study is to investigate the effect of endurance training with garlic and stevia supplementation on AgRP and α-MSH in the brain tissue of obese Wistar rats. Methods: ۳۶ obese male Wistar rats fed with a high-fat diet (۲۴ g fat, ۲۴ g protein, and ۴۱ g carbohydrate/۱۰۰ g) were divided into six groups, including: ۱) sham; ۲) stevia supplementation; ۳) garlic supplementation; ۴) endurance training; ۵) stevia supplementation plus endurance training, and ۶) garlic supplementation plus endurance training. Moreover, ۶ rats were included in the healthy control group to investigate the effects of obesity on the research variable. Training groups performed incremental endurance training for ۱۵-۵۰ minutes at a speed of ۱۵-۲۵ m/min, for eight weeks. Garlic and stevia supplements were added to the diet of the supplementation groups at a dose of ۲۵۰ mg/kg. Results: Levels of AgRP in stevia supplementation group were significantly higher than endurance training (P=۰.۰۱۹) and endurance training plus stevia supplementation (P=۰.۰۱۸) groups. Levels of α-MSH in the garlic supplementation (P=۰.۰۰۱), endurance training (P=۰.۰۰۲), stevia supplementation plus endurance training (P=۰.۰۰۱), and garlic supplementation plus endurance training (P=۰.۰۰۱) groups were significantly higher than the sham group. In addition, in the endurance training plus stevia supplementation group, the levels were significantly higher than the stevia supplementation group (P=۰.۰۰۲). Conclusion: Endurance training plus garlic supplementation as well as endurance training plus stevia supplementation seem to play a synergistic role in appetite control protein; however, more studies on AgRP changes, following training and garlic and stevia supplementation are needed.
نویسندگان
Mahsa Taleshi
Department of Physical Education and Sport Science, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran;
Reza Rezaeeshirazi
Department of Physical Education and Sport Science, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran;
Seyed Javad Ziaalhagh
Department of Physical Education and Sport Science, Shahrood Branch, Islamic Azad University, Shahrood, Iran.
Habib Asgharpour
Department of Physical Education and Sport Science, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran;
مراجع و منابع این مقاله:
لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :