The effect of ۸ weeks aerobic exercise training on cardiovascular risk factors in men with type ۲ diabetes mellitus

Introduction: Individuals with diabetes are often diagnosed with low high-density lipoprotein cholesterol (HDL-C) concentration, hypertriglyceridemia and development of cardiovascular disease (CVD). The purpose of this study was to determine the impact of aerobic training on blood profile and inflammatory marker (CRP) of type ۲ diabetes mellitus (T۲DM) people.Methods: Thirty diabetic males were recruited (age: ۵۰.۳۴ ± ۱۰.۲۸ years) and randomly assigned to ۸ weeks aerobic exercise training (n = ۱۵) and control groups (n = ۱۵). Before and after training blood pressure, weight, lipid profile (Total cholesterol [TC], triglyceride [TG], low-density lipoprotein cholesterol (LDL-C), HDL-C) and high-sensitivity C-reactive protein (hs-CRP) were measured. Exercise training was in mode of walking and consisted of ۵ exercise sessions/week at ۵۰%–۷۰% heart rate maximum and began with ۲۵ minutes of walking. Training increased each week by ۵ minutes until ۶۰ minutes of walking was reached. Each exercise session included approximately ۱۰ minutes of warm-up and cool-down periods.Results: Resting systolic blood pressure decreased following ۸ weeks of aerobic training (pre ۱۳۹ ± ۱۶ vs post ۱۲۱ ± ۱۱ mm Hg, P = ۰.۰۴). Also, TG significantly decreased (pre ۲۱۰.۱۹ ± ۹.۳۱ vs ۱۹۱.۱۲ ± ۷.۲۵, P = ۰.۰۳) and HDL-C significantly increased (pre ۴۲.۳۷ ± ۳.۱۵ vs ۴۷.۵۶ ± ۲.۱۹, P = ۰.۰۱) after exercise training. However, there was no difference between groups in TC, LDL-C, body mass index (BMI) and weight. In addition, a decrease in fasting blood glucose levels showed a significant difference between groups (pre ۱۴۲.۴۳ ± ۷.۹۶ vs ۱۲۱.۱۷ ± ۸.۳۲, P = ۰.۰۴).Conclusion: Regular aerobic exercise training can improve the lipid profile and reduce the cardiovascular risk factors in T۲DM patients. Exercise, like walking, is inexpensive and has relatively few negative side effects when performed properly.

کلیدواژه ها:

aerobic exercise ، Cardiovascular risk factors ، Type ۲ diabetes mellitus