The Effect of Aqueous Extract of Boswellia on Spatial Learning and Memory in Adult Male Rats

Background and Objective: Learning is the acquisition of information about the world and memory is a mechanism to encode, store and retrieve the learned information. Weak memory and learning disorders are the most common cognitive problems. In the present study, the pharmacological effects of aqueous extract of Boswellia on learning and spatial memory in male rats was investigated using the Morris water maze (MWM) test. Materials and Methods: In this experimental study, ۲۱ male rats were divided into ۳ groups including a control group (distilled water) and two groups treated with aqueous extract of Boswellia (۵۰ and ۱۰۰ mg/kg) that received the treatment for ۴ weeks. To evaluate learning ability of animals, Morris Water Maze was used. Results: In the first and the last day of training, all groups showed significant reduction in escape latency (P<۰.۰۰۰۱) and traveled distance (P<۰.۰۰۰۱). 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Keywords: Boswellia ، Spatial memory ، Morris water maze test