Afsoon Fazlinezhad - Department of Cardiology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran-Cardiovascular Research Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
Mona Adibian - Department of Cardiology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran
Ali Azari - Cardiovascular Research Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran- Department of Cardiac Surgery, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran
Leila Bigdelu - Department of Cardiology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran-Cardiovascular Research Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran

Background: Exercise echocardiography is a well-validated technique for the diagnosis of coronary artery disease. In addition to thediagnostic role, it also provides useful prognostic information. Objectives: The aim of this cross sectional study was to assess the prognosis of patients with negative exercise echocardiographic resultsover a one-year period follow-up. Patients and Methods: The outcomes of 336 patients who had normal exercise echocardiograms were examined. All clinical and exerciseechocardiogram parameters were recorded. Patients were followed up for 1 year. End points were defined as cardiac death, non-fatalmyocardial infarction, hospital admission for coronary artery disease, and coronary revascularization. Results: Mean age was 54.55 ± 10.34 years. 63.4 % were women. The most frequent risk factor was hypertension. There was no significantstatistical difference between men and women regarding the prevalence of systemic hypertension, diabetes mellitus, and historyof coronary artery bypass grafting. 5.67% of men and 8.9 % of women had positive exercise tolerance test for ischemia. Hemodynamicparameters, diastolic function, severity of mitral regurgitation, pulmonary artery pressures, peak strain rate were not significantlydifferent between men and women, but rest strain rates were significantly lower in women. Total exercise times and exercise capacitywere higher in men. After a 1-year follow-up there was no cardiac events and mortality. Conclusions: Patients with normal exercise echocardiogram results regardless of ischemia or chest pain during the test had excellentoutcomes over a one-year follow-up.

Outcome assessments; Exercise; Echocardiography; Prognosis