Antibacterial Effect of Thymus kotschyanus Boiss Leaves Extract on Some Gram-Negative Bacteria
- سال انتشار: 1398
- محل انتشار: فصلنامه عفونت، اپیدمیولوژی و پزشکی، دوره: 5، شماره: 2
- کد COI اختصاصی: JR_IEM-5-2_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 352
نویسندگان
Ph.D.Department of Biology, Faculty of Science, Farhangian University, Qom, Iran
چکیده
The use of medications with plant origin covers a wide variety of maladies and constitutes an alternative way to antibiotic therapy, which seems to be no longer promisingdue to the widespread antibiotics resistance among the pathogenic microorganisms. Active principles having antimicrobial activity could be extracted and purified from plantsand used in developing new medications. Among several diseases which have historically scourged man, some of the gram-negative bacteria are potentially epidemic and considered as one of the most outstanding causes of diarrhea. Therefore, this study aimed to evaluate the antibacterial activity of Thymus kotschyanus extracts.Materials & Methods: The antimicrobial effect of T. kotschyanus Boiss leaves extract on some gram-negative bacteria strains was assayed in vitro by the disk diffusion technique.Dried and crushed plant materials were extracted from distilled water by evaporation and distillation. Finally, the antimicrobial assays were carried out for the plant, and the resultswere compared with an ampicillin disk results. Findings: Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhimurium, Entrobacter cloacae, Proteus mirabilis, and Shigella dysenteriae were apparently killed by the extract, as judged by the presence of growth inhibition halos in the assays. The results of minimum inhibitory concentrations (MICs) showed that E. coli and E. cloacae strains were better inhibited by the extract. Conclusion: The above results were similar to those from ampicillin disk, suggesting that T. kotschyanus Boiss could be used as a source of active principles against some gram-negative bacteria. Therefore, the tested Thymus extract could be considered as a valuable natural antibacterial source, which seems to be applicable in both medicine and food industry.کلیدواژه ها
Antibacterial effects, Plant extraction, Gram-negative bacteriaمقالات مرتبط جدید
- چالش های برخی گیاهان دارویی استان کهگیلویه و بویراحمد
- Evaluation of Candida auris Colonization using Clinical Skin Swabs: A Single-Center Study in Isfahan, Iran
- Support and Practice of Smoke-Free Eating Places in Sarawak, Malaysia: A Structural Path Analysis
- Rate and Causes of Claim Denials in Iranian Hospitals: A Systematic Review and Meta-analysis
- The Effect of Impulsivity on Addition and Addictive Tendencies: A Meta-analysis
اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.