Evaluation of NT-ProBNP and Procalcitonin as Markers from Rodents with Myocardial Toxoplasmosis Using ECL Method: A Pilot Study
- سال انتشار: 1397
- محل انتشار: فصلنامه عفونت، اپیدمیولوژی و پزشکی، دوره: 4، شماره: 4
- کد COI اختصاصی: JR_IEM-4-4_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 395
نویسندگان
Parasitology Department, Medical Sciences Faculty, Tarbiat Modares University, Tehran, Iran
Parasitology Department, Medical Sciences Faculty, Tarbiat Modares University, Tehran, Iran
Parasitology Department, Medical Sciences Faculty, Tarbiat Modares University, Tehran, Iran
چکیده
Aims Toxoplasma parasites that extracted from different rodents are the same in immunologic and morphological characteristics but different in pathogenic characteristics. We found that the serum levels of ProBNP and Procalcitonin markers are high among these rodents. The aim of this study was the assessment of the serum levels of ProBNP and Procalcitonin markers among the rodents with myocardial toxoplasmosis. Materials & Methods In this study, we collected 286 rodents and extracted 250g of their hearttissues and blood samples to obtain DNA of T. gondii. We detected the positive samples, using the nested PCR method. Then, we examined serum levels of Pro BNP and Procalcitonin markers, using Electro Chemo Luminescence method (ECL) for assessment of myocardial toxoplasmosis in this host. Data analysis was also conducted by the statistical analysis method. This study was performed from January to March 2017, based on the prevalence study. Findings In this study, 68/286 samples of rodents were positive for GRA6 gene and these positive samples had high levels of Pro BNP and Procalcitonin markers that indicated myocardial toxoplasmosis and acute inflammation among these animals. Conclusion In this study, we found that the GRA6 gene was very useful to follow up toxoplasmosis in the rodents of the Golestan province, northeast of Iran. Also, ProBNP and Procalcitonin markers were at high levels in myocardial toxoplasmosisکلیدواژه ها
Toxoplasmosis; Rodents; GRA6 Gene; Pro BNP Marker; Procalcitoninمقالات مرتبط جدید
- چالش های برخی گیاهان دارویی استان کهگیلویه و بویراحمد
- Evaluation of Candida auris Colonization using Clinical Skin Swabs: A Single-Center Study in Isfahan, Iran
- Support and Practice of Smoke-Free Eating Places in Sarawak, Malaysia: A Structural Path Analysis
- Rate and Causes of Claim Denials in Iranian Hospitals: A Systematic Review and Meta-analysis
- The Effect of Impulsivity on Addition and Addictive Tendencies: A Meta-analysis
اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.