Sentinel node mapping for early breast cancer patients using 99mTc-phytate: Single center experience on 165 patients

سال انتشار: 1391
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 379

فایل این مقاله در 5 صفحه با فرمت PDF قابل دریافت می باشد

این مقاله در بخشهای موضوعی زیر دسته بندی شده است:

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_IRJNM-20-2_004

تاریخ نمایه سازی: 21 بهمن 1398

چکیده مقاله:

Introduction: Several radiotracers are being used for sentinel node mapping in patients with breast cancer. In the current study, we reported our experience with 99m-Tc Phytate for sentinel node mapping in Mashhad University of Medical Sciences. Methods: All breast cancer patients who underwent sentinel node mapping using 99m-Tc Phytate were included. All patients received intradermal peri-areolar injection of 0.5 mCi/0.1cc 99m-Tc Phytate. Lymphoscintiraphy was performed for 145 patients 5-10 minutes post-injection. The sentinel nodes were found during surgery using a hand-held gamma probe as well as blue dye technique. Results: In total 165 patients were evaluated. Lymphoscintigraphy showed axillary sentinel nodes in 135 out of 145 patients (93%) following imaging. At least one sentinel node could be detected in all these 135 patients during surgery. In the remaining 10 patients with sentinel node non-visualization, 5 had sentinel node harvesting failure during surgery. Median number of sentinel nodes on the lymphoscintigraphy images was 1. Sentinel node detection rate was 95% (157/165). In the 8 patients with sentinel node harvesting failure, 7 had pathologically involved axilla. Median number of harvested sentinel nodes was 1. Mean sentinel node to background count ratio was 10±2. Conclusions: 99m-Tc Phytate is an effective and highly successful radiotracer for sentinel node mapping. Sentinel node can be visualized in a short time after 99m-Tc Phytate injection on the lymphoscintigraphy images. The sentinel to background count during surgery is high which results in more convenient sentinel node harvesting and high detection rate.

نویسندگان

Vahid Reza Dabbagh Kakhki

Nuclear Medicine Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Ali Jangjoo

Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Alireza Tavassoli

Endoscopic and Minimally Invasive Surgery Research Center, Faculty of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

Mahdi Asadi

Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Wiatrek R, Kruper L. Sentinel lymph node biopsy indications and ...
  • Kaviani A, Noveiry BB, Noaparast M. Sentinel lymph node biopsy ...
  • Iida S, Haga S, Yamashita K, Yanagihara K, Kurita T, ...
  • Bekker J, Meijer S. The historical perspective of the sentinel ...
  • Carmon M, Olsha O, Schecter WP, Raveh D, Reinus C, ...
  • Sadeghi R, Zakavi SR, Forghani MN, Aryana K, Kakhki VR, ...
  • Sadeghi R, Forghani MN, Zakavi SR, Jangjoo A, Shabani GA, ...
  • Eftekhari M, Beiki D, Fallahi B, Arabi M, Memari F, ...
  • Sadri K, Ayati NK, Shabani G, Zakavi SR, Sadeghi R. ...
  • Aliakbarian M, Memar B, Jangjoo A, Zakavi SR, Reza Dabbagh ...
  • Momennezhad M, Zakavi SR, Dabbagh Kakhki VR, Jangjoo A, Ghavamnasiri ...
  • Eshima D, Fauconnier T, Eshima L, Thornback JR. Radiopharmaceuticals for ...
  • Subramanian G, McAfee JG, Mehta A, Blair RJ, Thomas ED. ...
  • Alavi A, Staum MM, Shesol BF, Bloch PH. Technetium-99m stannous ...
  • Tavares MG, Sapienza MT, Galeb NA Jr, Belfort FA, Costa ...
  • Ege GN, Warbick A. Lymphoscintigraphy: a comparison of 99Tc(m) antimony ...
  • Campbell J, Bellen JC, Baker RJ, Cook DJ. Technetium-99m calcium ...
  • Sadeghi R, Forghani MN, Memar B, Rajabi Mashhadi MT, Dabbagh ...
  • Takei H, Suemasu K, Kurosumi M, Ninomiya J, Horii Y, ...
  • Abdollahi A, Jangjoo A, Dabbagh Kakhki VR, Rasoul Zakavi S, ...
  • Dordea M, Colvin H, Cox P, Pujol Nicolas A, Kanakala ...
  • Arzoumanian A, Rosenthall L, Seto H. Clinical comparison of 99mTc-labeled ...
  • نمایش کامل مراجع