Cryotherapy for Keloids

Colloid or hypertrophic scar develops during the repair process following excessive dermis fibrosis. Hypertrophic and colloidal scars are one of the therapeutic problems that can sometimes be frustrating for both the physician and the patient. Various treatments have been offered to resolve this problem, which suggests that there is still no very effective and reliable treatment for this problem.Cryotherapy is an effective way to treat small hypertrophic scars such as acne scars. Combined treatment with cryotherapy plus intra-steroid injection is one of the most common and common treatment modalities for the treatment of hypertrophic and keloid scars. The efficacy of treatment after two sessions of treatment has been reported in studies ranging from 30 to 70%. It is recommended that a one-month interval between treatments be allowed to allow the skin to recover after this procedure. Cryotherapy is performed by contact with liquid nitrogen or by spray. One of the inevitable side effects of these treatments is temporary or permanent hypopigmentation of the skin.Intraoperative cryotherapy is a relatively new treatment that uses a double sells needle to transfer liquid nitrogen into the central colloidal nucleus. Although studies in this field are limited, according to the available literature, this method seems to be preferable to contact cryotherapy, in that the rate of colloid volume reduction in this method is about 63%, which is approximately 20%, this method is more effective. Also, in terms of side effects, it has been reported that hypopigmentation or depigmentation after intra-lesion chemotherapy is less than contact therapy. Reports of treated patients reported no recurrence of colloid following intrathecal cryotherapy for 6 months. Few studies are comparing this treatment with other methods of colloid therapy, but in one study comparing this method with surgery and radiotherapy, the authors noted that the therapeutic results were poorer in the method of cryotherapy