Ramin Javahershenas - Faculty of Chemistry, Urmia University, Urmia, Iran
Jabbar Khalafy - Faculty of Chemistry, Urmia University, Urmia, Iran
Rolf Prager - Department of Chemistry, Flinders University, Adelaide, Australia

This review provides an overview of the recent literature on application of arylglyoxals the synthesis of pyrrolo[2,3-d]pyrimidines via multicomponent reactions in the period of 2008–2018. 1,2-Dicarbonyl compounds are attractive precursors for synthesis of various heterocyclic compounds, and arylglyoxals are frequently applied in synthesis of various organic compounds, and in particular of pyrrolo[2,3-d]pyrimidines derivatives, which are important due to their biological and pharmaceutical activities.

Arylglyoxals, Pyrrolo[2,3-d]pyrimidines, Multicomponent reactions, Enamines