Update on Diagnosis and Management of Polycystic Ovarian Disease

PCOS is thought to be one of the most common endocrinopathies in women, affecting 5 to 12 percent of women. The syndrome is characterized clinically by oligomenorrhea and hyperandrogenism, as well as the frequent presence of associated risk factors for cardiovascular disease, including obesity, glucose intolerance, dyslipidemia, fatty liver, and obstructive sleep apnea.Main Results and the Role of Chance:The evidence in the assessment and management of PCOS is generally of low to moderate quality. The guideline provides 31 evidence-based recommendations, 59 clinical consensus recommendations, and 76 clinical practice points all related to assessment and management of PCOS. Key changes in this guideline include: 1) Considerable refinement of individual diagnostic criteria with a focus on improving accuracy of diagnosis; 2) Reducing unnecessary testing;3) Increasing focus on education, lifestyle modification, emotional wellbeing and quality of life; and 4) Emphasizing evidence based medical therapy and cheaper and safer fertility managementTotal rule of treatment• Amelioration of hyperandrogenic features • Management of underlying metabolic abnormalities and reduction of risk factors for type 2 diabetes • Prevention of endometrial hyperplasia and carcinoma • Contraception for those not pursuing pregnancy• Ovulation induction for those pursuing pregnancy