Whole grain consumption does not affect obesity measures: an updated systematic review and meta-analysis of randomized clinical trials

Background and Objective: To update previous meta-analysis, since the release of a previous meta-analysis on the effect of whole grain (WG) intake on obesity measures, several clinical trials were published. Materials and Methods: We searched the online databases for relevant studies published up to Feb 2019, using relevant keywords. Randomized clinical trials investigating the effect of WG products or diets high in whole-grain foods, compared with a control diet, on anthropometric measures (including body weight, BMI, waist circumference (WC) and fat mass) were included. Findings: In total, 21 studies with a total sample of 1798 participants, aged ≥18 years, were considered. Based on 22 effect sizes from 19 studies on body weight, with a total sample of 1698 adults, we found no significant effect of WG consumption on body weight. The same findings were obtained for BMI. With regards to body fat percentage, fat mass, fat free mass and WC, we failed to find any significant effect of WG consumption. Conclusion: Our findings did not support current recommendations of WG intake in attempts to control obesity measures. Given the beneficial effects of WG intake on other measures of human health, additional well-designed studies are required to further investigate the effect on obesity.

کلیدواژه ها:

Whole grains ، obesity ، anthropometry ، meta-analysis ، clinical trials