Environmental Metabolomics: A New Era in Environmental Chemistry

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 310

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شناسه ملی سند علمی:

NSCEI09_005

تاریخ نمایه سازی: 19 آبان 1398

چکیده مقاله:

The rapid development of „omics‟ technologies has created the possibility of using these approaches to investigate the molecular complexity of biological and/or environmental systems [1]. Environmental metabolomics is one of the recent omics research area which can be defined as the study of the sources, reactions, transport, effects, and fates of chemical species in the air, soil, and water environments; and the effect of human activity and biological activity on these. In other words, this filed aims to study the living systems (e.g., plants) at the molecular level to provide a non-biased characterization of the metabolome of a plant‟s tissue in response to its environment [2]. Contaminants of emerging concern (CECs), such as pharmaceuticals and personal care products, have been increasingly detected in agricultural irrigation waters which can cause changes in plant morphology and plant metabolomic pathways [3]. On the other hand, as environmental metabolomics is collecting more data (volume) from different instruments such as chromatography and/or spectroscopy (variety), this journey becomes more challenging in terms of using the right data and the right tools to make the right decisions in real time (velocity). Chemometric methods are now filling this gap. Chemometric methods are coming of age as a family of methods that have been proposed for exploring, modelling, and interpreting important patterns in large data sets [4]. Chemometric methods based on multivariate data analysis and in multilinear and non-linear models attempt to explore, model, identify and interpret the most important patterns present in the different metabolomics data arrays by means of new mathematical and software tools. In this contribution, the role of environmental metabolomics in current environmental chemistry studies will be discusses. Additionally, the role of chemometrics in this regard will be examined.

نویسندگان

Hadi Parastar

Department of Chemistry, Sharif University of Technology, Tehran, Iran