Treatment of Polycystic Ovary Syndrome with Genetic Methods

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 409

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شناسه ملی سند علمی:

COBGY15_168

تاریخ نمایه سازی: 11 آبان 1398

چکیده مقاله:

Background and Aim: Polycystic disease is a common disease in women and is the most common cause of infertility due to ovulation failure. The primary goal of the treatment is to return the ovulation. Today s studies are based on finding a genetic test that consists of several genetic differences in the determination of drug dosages for patients. The purpose of this study was to investigate the treatment of polycystic ovary syndrome with genetic methods.Methodology: The study was conducted as a review of several articles between 2010 and 2019. The review was conducted in the journal and databases pubmed, scincedirect, elsiver, proqust, willy, spinger, google scular with key words such as treatment, polycystic ovary syndrome with genetic methods. The results were analyzed and graded as a schematic.Results: The findings indicate that genetic changes in the gene of the vitamin D receptor can be important in the progression of the disease. Many studies have been conducted to investigate the association of taqI polymorphism in the vitamin D receptor gene in polycystic ovary syndrome. But there is still no definitive association between the Tt, Tt, TT genotypes with FSH, testosterone and progesterone, and research is still ongoing. Therefore, there is still no link between taqI polymorphism and polycystic ovary syndrome.Conclusion: There are many new therapies on polycystic ovary syndrome. With the development of genetic therapy, great changes can be made in improving the health of patients.

نویسندگان

Mehri Kalhor

PhD Student in Reproductive Health, Tarbiat Modarres University

Fatemeh Samii rad

Pathologist, Associate Professor, Qazvin University of Medical Sciences

Leila Shafikhani

Bachelor of Operating Room Technician, kowsar hospital, Qazvin University of Medical Sciences