Study of the Role of Selenium in Preventing Breast Cancer

Backgrounds: Breast cancer is the second most common cancer in women. Selenium is an antioxidant, a micronutrient, which may have a protective role against breast cancer, possibly due to transcriptional effects and cellular proliferation. Considering the prevalence of breast cancer in our country and the anti-cancer effect of selenium, we decided to examine the relationship between these two components Material and method : This systematic review examines and summarizes numerous articles from databases and authored scientific sites pubmed, sid, scopus, magiran and the search engine googlescholar and science net with the keywords of breast cancer, selenium, prevention. Over the past five years. In this study, descriptive, analytical and interventional articles have been used.Result: Studies have shown that selenium can play a role in preventing breast cancer and can reduce mortality in people with this cancer. By increasing the serum level of selenium by 1 unit, the risk of breast cancer is reduced by 7%. Selenium oxide can inhibit the growth of cancer cells through cell death .Conclusion: according to studies , Selenium is a preventative and therapeutic agent in breast cancer. Selenium, according to its functional characteristics, can prevent the progression of the disease and the growth of more cancer cells. As a result, the inclusion of this natural substance in the diet of individuals is recommended