The Effect of Traditional Medicine on Epilepsy Treatment

Epilepsy is one of the chronic neurological disorders. Today, more than 70 million people in the world are suffering from epilepsy using modern Western medicine. However, about 30-40% of patients are resistant to drugs and suffer from complications. A search in twoPubMed and Google Scholar databases was conducted in the last five years, with a total of 84 articles found Regarding their relationship with the subject, 23 articles were examined. The results of this study were from traditional Iranian and Chinese medicine. For example,by reviewing some of the most important botanical sources in Iran, such as Canon, al-Hawi, al-Abniah ‘an Haqaeq al Adwia, Tuhfat al-Mu’minin, and Makhzan ul-Adwia, several herbs as herbal remedies for the treatment of epilepsy is identified. Traditional ChineseMedicine (TCM), which has been used centuries ago for the prevention and even treatment of epilepsy in China. The compounds obtained from the plants have antiinflammatory, antiseptic, and anticoagulant properties that have been shown to be positive in in vivo and invitro experiments. In these compounds, the presence of Flavonoids, Furanocoumarins and Terpenoides is observed, which causes anticonvulsant effects in these plants. Gastrodin, Asarone, Rhynchophylline, Curcumin, etc are Chinese medicine monomers that, byregulating neuronal receptors, expressing inflammatory factors, express the apoptotic protein with anti-epileptic effects. Conclusion: Therefore, due to the severe side effects of the use of commonly used chemical drugs, as well as the efficacy of traditional medicine and herbs in epilepsy treatment, medicinal herbs can be the basis for discovering new antiepileptic drugs.