Evaluating the Association of Trigeminal Neuralgia and Diabetes Mellitus: A Retrospective Study

this study is designed to evaluate the relationship between diabetes mellitus (DM) and trigeminal neuralgia (TN), in order to provide newinsight for TN pathogenesis. Materials and Methods: This retrospective cross sectional study compared the prevalence of DM in patients with trigeminal neuralgia and healthy patients without TN during 2007-2018. In both TN patients and control group, 193 participantswere enrolled. These participants were the patients who referred to the Oral and Maxillofacial Medicine Department of the Dentistry School of Shiraz University of Medical Sciences. The age and sex of both groups were matched. Diabetes mellitus (type 1 and 2) wasdiagnosed based on their reports and routine requested lab test (fasting blood sugar, 2hours post prandial). Odds ratio and chi square test were used to compare mean values. Results: The prevalence of DM in TN patients and Control group was 11.4% and 9.8%. The mean ageof participants were 56.96 ± 13.66 and 56.46 ±13.47 in TN patients and Control group. The difference of TN prevalence between both groups was not significantly different (P- value = 0.62). Conclusion: Although the prevalence of DM in patients with TN was higher than control group, the difference was not significantly different (P- value > 0.05). Evaluated women with TN, expressed DM 25% more than men affected by TN.