Use of iPSC Derived Brain Cells to Model Neurode-generative Disorders

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 329

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شناسه ملی سند علمی:

RROYAN20_023

تاریخ نمایه سازی: 29 مهر 1398

چکیده مقاله:

Despite major advances in our understanding of neurodegenera-tive disorders, no efficient therapies are available for patients with dementia, motor neuron disease and other neurodegenerative dis-orders. With the advent of pluripotent stem cells (PSCs) it now becomes possible to better model human disease in vitro (and in humanized mice), which may lead to the development of novel therapies for these currently untreatable disorders. Data will be presented on how to build such models, and how to use PSC-de-rived cells to identify novel therapeutic targets and therapies.

نویسندگان

J Garcia Leon

KU Leuven Stem Cell Institute, Belgium

CH Claes

KU Leuven Stem Cell Institute, Belgium

JVD Daele

KU Leuven Stem Cell Institute, Belgium

R Furtado

KU Leuven Stem Cell Institute, Belgium