Examine of Thyroid Function in Pediatric Nephrotic Syndrome; Tehran-Iran

سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 316

فایل این مقاله در 7 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_INJPM-3-2_009

تاریخ نمایه سازی: 20 مهر 1398

چکیده مقاله:

Introduction In children with nephrotic syndrome, it is probable to determine a hypothyroid state because of thyroxine (T4), tri-iodothyronine (T3) and thyroid-binding globulin loss in presence of proteinuria. Objectives: To examine thyroid function in pediatric cases of nephrotic syndrome. Methods: In a cross-sectional study, from march 2010 to march 2012, thyroid function tests were performed in 104 patients referred to the nephrology department of children’s medical center, because of nephrotic  syndrome. Collected data analyzed with SPSS Statistics 17 and pResults: Sixty one cases identified as hypothyroid patients and were treated with supplementary levothyroxine. There were 41 (67.2%) males and 20 (32.8%) females with the mean age of 3.72±3.35 years. Our patients showed lowered T3 (68.3%) and T4 (64.4%) in comparison with normal values. Median TSH (Thyroid-stimulating hormone) was 11.65±6.71 Micu/ml and 2.82±0.82 in the hypothyroid and euthyroid patients respectively. In all, TSH was negatively correlated with the total urinary protein content . Conclusions: According to this study, the occurrence of hypothyroidism in any child with nephrotic syndrome needs to be mentioned. It is proposed to systematically search hypothyroidism by measuring TSH and free T4 in these patients particularly when proteinuria is prolonged.

نویسندگان

Niloofar Hajizadeh

Associated profesor of pediatric nephrology. Children’s Medical Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran

Sayed Mahdi Marashi

Trauma Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Behnam Nabavizadeh

Pediatric Urology Research Center, Pediatric Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran.

Ehsan Elhami

Resident of ophthalmology. Khatam Hospital, Mashhad University of Medical Sciences, Mashhad, Iran

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • Karen J. Markdante, etal. Nelson Essentials of pediatrics 6th Edition. ...
  • Trouillier S, Delèvaux I, Rancé N, André M, Voinchet H, ...
  • Afrasiabi MA, Vaziri ND, Gwinup G, et al. Thyroid function ...
  • Fonseca V, Thomas M, Katrak A, Sweny P, Moorhead JF. ...
  • Hoffman AS, Arem R, Eknoyan G. Thyroid Function in Renal ...
  • Kelly  G. Peripheral metabolism of thyroid hormones: a Review. Alternative ...
  • Sawant SU, Chandran S, Almeida AF, Rajan MG. Correlation between ...
  • Afroz S, Khan AH, Roy DK. Thyroid function in children ...
  • Mattoo TK. Hypothyroidism in infants with nephrotic syndrome. Pediatr Nephrol. ...
  • McLean RH, Kennedy TL, Rosoulpour M, Ratzan SK, Siegel NJ, ...
  • Ghadiri K, Darbandi M, Khodadadi L, Khademi N, Rahimi MA, ...
  • Seyfhashemi M, Ghorbani R, Alavi M. Prevalence of Goiter and ...
  • Ito S, Kano K, Ando T, Ichimura T. Thyroid function ...
  • Harton PY, Wemeau JL, Guillemin R, Raviart B, Vanhille P, ...
  • Wilschanski M, Hirsch HJ, Algur N, Drukker A. Abnormal thyroid ...
  • Kapoor K, Saha A, Dubey NK, Goyal P, Suresh CP, ...
  • Burke CW, Shakespear RA. Triiodothyronine and thyroxine in urine. Renal ...
  • Gilles R, den Heijer M, Ross AH, Sweep FC, Hermus ...
  • Abid A, Khaliq S, Shahid S, Lanewala A, Mubarak M, ...
  • Gavin LA, McMahon FA, Castle JN, Cavalieri RR. Alterations in ...
  • Basiratnia M, Yavarian M, Torabinezhad S, Erjaee A. NPHS2 Gene ...
  • Feinstein EI, Kaptein EM, Nicoloff JT, Massry SG. Thyroid function ...
  • Guo QY, Zhu QJ, Liu YF, Zhang HJ, Ding Y, ...
  • Liu H, Yan W, Xu G. Thyroid hormone replacement for ...
  • Kapoor K, Saha A, Dubey NK, Goyal P, Suresh CP, ...
  • نمایش کامل مراجع