Oral manifestations as good tools for diagnosis and monitoring activity of Crohn disease (a review of literatures)

Introduction: Crohn disease is a chronic granulomatous inflammatory disorder that can affect any part of the gastrointestinal tract from the mouth to the anus with the most common localization in the ileocecal region. The prevalence of oral lesions in Crohn disease patients vary over a wide range from 5% to 20% due to contradictory data. Oral Crohn disease may precede the intestinal manifestations or may be present at the same time after the occurrence of the gastrointestinal symptoms Method: Fifteen papers were found in a research conducted in the PubMed and google scholar search engine with keywords: oral manifestation, diagnosis, Crohn disease from 1996 to 2018. Results: Indurated tag-like lesions, cobblestoning, mucogingivitis, aphthous stomatitis, and pyostomatitis vegetans are the main oral presentations of Crohn disease. These oral manifestations may aid in the diagnosis and the monitoring of disease activity, whilst ignoring them may lead to an inaccurate diagnosis and useless and expensive workups.Conclusion: The data have shown that Oral Crohn disease is important in the diagnosis of Crohn disease due to its easy access during physical examination, characteristic clinical features, and can commonly harbor diagnostically useful material for histopathological examination.

کلیدواژه ها:

oral manifestation ، diagnosis ، Crohn disease.