(Carboxy-3-oxopropylamino)-3-propylsilylcellulose as a novel organocatalyst for the synthesis of coumarin derivatives under solvent-free conditions

In this research, (Carboxy-3-oxopropylamino)-3-propylsilylcellulose (COPAPSC) as an organocatalyst, has been synthesized by grafting of succinic anhydride on the NH2-modified cellulose (cellulose functionalized with 3- aminopropyltriethoxysilane). The –CO2H group-functionalized cellulose (COPAPSC) is used as a catalyst for the synthesis of coumarin derivatives from the reaction of phenolic substrate and β- Keto-esters under solvent-free conditions. The results showed that the yield of products is between 85-94%. The advantages of this reaction include simple work-up, short reaction time, excellent yields as well as easily separation of catalyst. The catalyst can be reused several times in subsequent reactions without any decreasing in the catalyst reactivity.

کلیدواژه ها:

(Carboxy-3-oxopropylamino)-3-propylsilylcellulose ، Solvent-free condition ، Phenolic substrate ، β- Keto-ester