Mohammad Reza Poor Heravi - Department of Chemistry, Payame Noor University, Abhar, Iran
Hassan Karami - Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۳۶۹۷, Tehran, IRAN
Bagher Mohammadi - Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۳۶۹۷, Tehran, IRAN
Vahid Azizkhani - Department of Chemistry, Payame Noor University, PO Box ۱۹۳۹۵-۳۶۹۷, Tehran, IRAN

An efficient and convenient synthesis of novel tetrahydrobenzo[c]acridin-8(7H)-one derivatives is described using the electrogenerated anion of acetonitriles as the base in the presence of tetrabutylammonium fluoride as an effective supporting electrolyte in a one-pot, three-component condensation of aromatic aldehyde, dimedone and 1-naphthyl amine. The reaction is carried out in an undivided cell containing an iron cathode and a graphite anode under a constant current density of 5 mA/cm2 (I=20 mA, electrode surface=5 cm2) in CH3CN at room temperature was found to be optimum for the electrochemically induced chain process and resulted in the highest yield. An efficient and convenient synthesis of novel tetrahydrobenzo[c]acridin-8(7H)-one derivatives is described using the electrogenerated anion of acetonitriles as the base in the presence of tetrabutylammonium fluoride as an effective supporting electrolyte in a one-pot, three-component condensation of aromatic aldehyde, dimedone and 1-naphthyl amine. The reaction is carried out in an undivided cell containing an iron cathode and a graphite anode under a constant current density of 5 mA/cm2 (I=20 mA, electrode surface=5 cm2) in CH3CN at room temperature was found to be optimum for the electrochemically induced chain process and resulted in the highest yield.

Electrolysis transformation, electrogenerated base, multicomponent reaction, acridine, dimedone, 1-naphthyl amine