Immunohistochemical Expression of Nuclear β-Catenin and STAT-6 in a Solitary Fibrous Tumor of the Soft Palate: A Case Report and Review of the Literature
عنوان مقاله: Immunohistochemical Expression of Nuclear β-Catenin and STAT-6 in a Solitary Fibrous Tumor of the Soft Palate: A Case Report and Review of the Literature
شناسه ملی مقاله: JR_IJP-12-3_014
منتشر شده در شماره 3 دوره 12 فصل در سال 1396
شناسه ملی مقاله: JR_IJP-12-3_014
منتشر شده در شماره 3 دوره 12 فصل در سال 1396
مشخصات نویسندگان مقاله:
Ivonne A. Montes-Mojarro - Surgical Pathology Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
Javier Baquera-Heredia - Surgical Pathology Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
Juan Felipe Sanchez-Marle - Head and Neck Surgery Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
Carlos Ortiz-Hidalgo - Surgical Pathology Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
خلاصه مقاله:
Ivonne A. Montes-Mojarro - Surgical Pathology Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
Javier Baquera-Heredia - Surgical Pathology Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
Juan Felipe Sanchez-Marle - Head and Neck Surgery Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
Carlos Ortiz-Hidalgo - Surgical Pathology Department, The American British Cowdray Medical Center, Mexico city ۰۱۱۲۰, Mexico
The solitary fibrous tumors (SFT) are rare tumors in the head and neck region and there have been only 5 cases reported in the literature in the soft palate. The current paper presents a unique case of a 62-year-old male with TFS arising in the soft palate. The tumor was highly cellular, composed of bland looking haphazardly arranged spindle cells. The signal transducer and activator of transcription (STAT)-6 and nuclear β-catenin were reactive by immunohistochemistry (IHC). The current case highlights the importance of the STAT-6 and the β-catenin as IHC markers to make a differential diagnosis with other entities. In summary, the paper presents the first reported case of a SFT of the soft palate in a male patient with nuclear expression of STAT-6 and β-catenin.
کلمات کلیدی: Solitary Fibrous Tumor (SFT), Immunohistochemistry (IHQ), Mesenchymal Tumors, Soft Palate, STAT-6, β-Catenin
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/930256/