Background: Infertility is considered as a major health care problem of different communities. The high prevalence of this issue doubled its importance. A significant proportion of infertility have been related to environmental conditions and also acquired risk factors. Different environmental conditions emphasized the need to study the different causes of infertility in each area.Objective: The aim of this study was to determine the frequency causes of infertility in infertile couples.Materials and Methods: In this cross sectional descriptive study 3603 infertile men and women that were referred to infertility clinic of Maryam infertility center in Beheshti Hospital during 2017 to 2018, were examined. This center is the only governmental center for infertility in Isfahan. Sampling was based on census method. Information about the patients was obtained from medical examinations and laboratory findings. To analyze the data, descriptive statistics such as frequencies and the mean were used.Results: The prevalence of primary and secondary infertility was 71.43% and 28.57% respectively. The etiology of infertility in couples revealed; male factor in 22.2%, female factor in 50%, combined factors in 4.17% and undetermined cause in 23.61%. In the causes of female infertility, menstrual disorders, diseases (obesity, thyroid diseases, and diabetes), ovulation dysfunction, uterine factor, fallopian tubes and cervical factor had the highest prevalence respectively. The causes of male infertility based on their frequency included semen fluid abnormalities, genetic factors, vascular abnormalities, and anti-spermatogenesis factors, respectively.Conclusion:
Etiology pattern of infertility in our study is similar with the many other patterns that have been reported by the World Health Organization. This study showed that in central part of Iran (Isfahan province), female factor as the main cause of infertility (50%). Therefore, there is a need to revise public health program on infertility to focus on the education and prevention of infertility and its risk factors.