Impact of intra-cytoplasmic morphologically selected sperm injection on ART outcome

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 362

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شناسه ملی سند علمی:

RMED08_016

تاریخ نمایه سازی: 21 مرداد 1398

چکیده مقاله:

Selecting best spermatozoa with good morphology during intra-cytoplasmic sperm injection (ICSI) is an important issue. In recent seventeen years improving ICSI using high magnification (x6000) results in establishing intra-cytoplasmic morphologically selected sperm injection (IMSI) method utilizing Nomarsky optic system for real time selecting free vacuole spermatozoa. Therefore, new criterion, motile sperm organelle morphology sperm examination (MSOME), had been developed to identify high quality spermatozoa based on cephalic vacuole and its number and size, head shape and size, acrosome integrity and irregularity of mid-piece under high magnification prior to oocyte injection. Some investigations claim that IMSI can improve embryo quality, implantation rate and pregnancy rate, and decrease miscarriage rate especially in patients with ART failure. Different types of opposition opinion have been emerged about the clinically advantages of IMSI, but almost believe that severe male factor and repeated implantation failure (RIF) patients could benefit from this method. Time consuming, high budget necessity and high skill for performing IMSI are the challenging items should be mentioned.

نویسندگان

Sh Ghazali

Islamic Azad University, Sanandaj Branch, Sanandaj, Iran

MA Khalili

Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Ar Talebi

Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran